"Meme" used to mean a self-replicating idea, but it seems to have been diluted so much that all it means now is something that you repeat by rote as a substitute for wit or humor. The Internet is so choked with these meaningless, unamusing endless repetitions that one despairs of finding real humor anymore. Why be witty when you can just plug something into a formula instead? After all, everything is funny if you print it over a picture of a cat, or insert it between "1)" and "2) ??? 3) Profit". Did we learn nothing from "all your base are belong to us"?
Don't get me wrong: there is such a thing as a running joke. But to be a running joke, first of all, it has to be a joke.